4-Nitrophenol, 99%, Thermo Scientific Chemicals

Description

4-Nitrophenol is used as a precursor to prepare phenetidine, acetophenetidne and pH indicator. Its carboxylate ester derivatives are involved as an active component for the construction of amide moieties in peptide synthesis. It is used as an intermediate in the synthesis of paracetamol and N-acetyl-p-aminophenol dyestuffs.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Nitrophenol is used as a precursor to prepare phenetidine, acetophenetidne and pH indicator. Its carboxylate ester derivatives are involved as an active component for the construction of amide moieties in peptide synthesis. It is used as an intermediate in the synthesis of paracetamol and N-acetyl-p-aminophenol dyestuffs.

Solubility
Freely soluble in alcohol, chloroform, ether. Freely soluble in acetone. Slightly soluble in water.

Notes
Incompatible with strong oxidizing agents and strong bases.

Specifications

Chemical Identifiers

• CAS: 100-02-7
• Molecular Formula: C6H5NO3
• Molecular Weight (g/mol): 139.11
• MDL Number: MFCD00007331
• InChI Key: BTJIUGUIPKRLHP-UHFFFAOYSA-N
• Synonym: p-nitrophenol, phenol, 4-nitro, paranitrophenol, niphen, 4-hydroxynitrobenzene, p-hydroxynitrobenzene, phenol, p-nitro, mononitrophenol, paranitrofenol, paranitrofenolo
• PubChem CID: 980
• ChEBI: CHEBI:16836
• IUPAC Name: 4-nitrophenol
• SMILES: OC1=CC=C(C=C1)[N+]([O-])=O

• Melting Point: 110°C to 115°C
• Density: 1.48
• Boiling Point: 279°C (decomposition)
• Flash Point: 169°C (336°F)
• Quantity: 250 g
• UN Number: UN1663
• Beilstein: 1281877
• Sensitivity: Light sensitive
• Merck Index: 14,6621
• Solubility Information: Freely soluble in alcohol,chloroform,ether; Freely soluble in acetone; Slightly soluble in water.
• Formula Weight: 139.11
• Percent Purity: 99%
• Chemical Name or Material: 4-Nitrophenol

Safety and Handling

Hazard Category	H301-H312+H332-H373-H500
Hazard Statement	GHS H Statement H373-H302-H312-H332 May cause damage to organs through prolonged or repeated exposure. Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled.
Precautionary Statement	P260-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P312-P314-P330-P363-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: NITROPHENOLS
EINECSNumber	202-811-7
RTECSNumber	SM2275000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only