Paxillin Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 100291IG150UL

Catalog No. 50-172-5980

Description

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.

Specifications

• Antigen: Paxillin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PXN
• Gene Alias: paxillin, PXN
• Host Species: Rabbit
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 1.2 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: P49023, Q8VI36
• Gene Symbols: PXN
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 19303, 5829
• Content And Storage: -20°C
• Form: Liquid