Piroxicam, Thermo Scientific Chemicals

Description

Piroxicam is an effective and potent inhibitor of prostaglandin synthesis and a Cox-1 and Cox-2 inhibitor. Studies show that Piroxicam blocks release of platelet ADP, and inhibits Cox-1 more potently than Cox-2.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Piroxicam is an effective and potent inhibitor of prostaglandin synthesis and a Cox-1 and Cox-2 inhibitor. Studies show that Piroxicam blocks release of platelet ADP, and inhibits Cox-1 more potently than Cox-2.

Solubility
Soluble in water, ethanol, chloroform, ethyl acetate.

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Specifications

Chemical Identifiers

• CAS: 36322-90-4
• Molecular Formula: C15H13N3O4S
• Molecular Weight (g/mol): 331.346
• MDL Number: MFCD00057317
• InChI Key: QYSPLQLAKJAUJT-UHFFFAOYSA-N
• Synonym: piroxicam, feldene, piroxicamum, pyroxycam, roxicam, piroftal, baxo, artroxicam, bruxicam, caliment
• PubChem CID: 54676228
• ChEBI: CHEBI:8249
• IUPAC Name: 4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-yl-1$l^{6},2-benzothiazine-3-carboxamide
• SMILES: CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=CC=CC=N3

• Color: Yellow
• Quantity: 10 g
• UN Number: UN2811
• Merck Index: 14,7506
• Solubility Information: Soluble in water,ethanol,chloroform,ethyl acetate.
• Formula Weight: 331.35
• Physical Form: Powder
• Chemical Name or Material: Piroxicam

Safety and Handling

Hazard Category	H301
Hazard Statement	GHS H Statement H301 Toxic if swallowed.
Precautionary Statement	P264b-P270-P301+P310-P330-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber	252-974-3
RTECSNumber	DL0705000
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only